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Articles

Paediatric trauma education in low- and middle-income countries: A systematic literature review

Jane A Rivas1, Joseph Bartoletti2, Sarah Benett3, Yukino Strong4, Thomas E Novotny5, Megan L Schultz1

1 Pediatric Emergency Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
2 Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
3 Department of Pediatrics, John Hopkin’s University, Baltimore, Maryland, USA
4 Medical College of Wisconsin, Milwaukee, Wisconsin, USA
5 Department of Epidemiology and Biostatistics, San Diego State University, San Diego, California, USA

DOI: 10.7189/jogh.12.04078

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Abstract

Background

Trauma-specific training improves clinician comfort and reduces patient morbidity and mortality; however, curricular content, especially with regard to paediatric trauma, varies greatly by region and income status. We sought to understand how much paediatric education is included in trauma curricula taught in low- and middle-income countries (LMICs).

Methods

We conducted a systematic literature review in October 2020 and in July 2022 based on PRISMA guidelines, utilizing seven databases: MEDLINE, Scopus, Web of Science, CINAHL, Cochrane Reviews, Cochrane Trials, and Global Index Medicus. Reports were limited to those from World Bank-designated LMICs. Key information reviewed included use of a trauma curriculum, patient-related outcomes, and provider/participant outcomes.

Results

The search yielded 2008 reports, with 987 included for initial screening. Thirty-nine of these were selected for review based on inclusion criteria. Sixteen unique trauma curricula used in LMICs were identified, with only two being specific to paediatric trauma. Seven of the adult-focused trauma programmes included sections on paediatric trauma. Curricular content varied significantly in educational topics and skills assessed. Among the 39 included curricula, 33 were evaluated based on provider-based outcomes and six on patient-based outcomes. All provider-based outcome reports showed increased knowledge acquisition and comfort. Four of the five patient-based outcome reports showed reduction in trauma-related morbidity and mortality.

Conclusion

Trauma curricula in LMICs positively impact provider knowledge and may decrease trauma-related morbidity and mortality; however, there is significant variability in existing trauma curricula regarding to paediatric-specific content. Trauma education in LMICs should expand paediatric-specific education, as this population appears to be underserved by most existing curricula.

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In 2019, the global prevalence of unintentional paediatric injuries was nearly 8.5 million, contributing to 1.02 million years of life lost due to disability [1]. In 2016, the World Health Organization (WHO) estimated that one million children die annually due to traumatic injuries [2,3]. Disproportionately, 90%-95% of these deaths occur in low- and middle-income countries (LMICs) [4]. The World Bank defines LMICs as countries with a per capita gross national income (GNI) of US$1036 to US$4045 [5].

A large body of research exists on how to improve trauma outcomes in LMICs. It focusses on methods of pre-hospital system development, overall system organization, improved availability of specialty care, and trauma care training [2,6]. Due to variability in regional needs and supplies, multiple courses have been developed [2,712]. Traditional courses, like Advanced Trauma Life Support (ATLS), are cost prohibitive, with a US$1000 price per student, fuelling the development of region-specific curricula. All courses demonstrate improvement in provider knowledge and skills and decreases in injury-related morbidity and mortality [2,6,13,14].

ATLS, Trauma Education and Management (TEAM), and Primary Trauma Care (PTC) are the most widely studied trauma curricula [2,9,1521]. However, these standardized teaching modalities may not translate to limited-resource settings due to variability in resources, differing epidemiology, and unique injury mechanisms [7,22]. Programme costs for instructors and materials also vary greatly, limiting a hospital’s ability to obtain the resources needed for training. Most courses focus on adult trauma, with little to no inclusion of paediatric-focused education. This neglects a significant portion of the global population. LMICs have a median age of 26.4 years compared to 41.5 years in high income countries [23]. Previous reviews have demonstrated this paucity of paediatric-specific trauma trainings in LMICs [24], but little is known about paediatric content in general trauma training. Given that paediatric injuries have a preventable death rate of nearly 32%, there needs to be a greater assessment of existing trauma curricula in order to optimize paediatric care [25].

To determine the degree of inclusion of paediatric trauma education in curricula taught in LMICs, we conducted a systematic literature review. We aimed to gather information on existing trauma curricula, compare their educational content, and review the amount and quality of paediatric topics incorporated in trauma trainings in LMIC. Our participants, intervention, comparison, outcome (PICO) question was aimed at low-resource settings and asked what is the best curriculum for teaching trauma assessment and management that is non-inferior, cost-effective, and sustainable when compared to traditional trauma curricula?

METHODS

A systematic review of the existing literature guided by the Preferred Reporting Items for Systematic Reports and Meta-analyses (PRISMA) statement [26] was performed in October 2020 and in July 2022. The review was not reported through the PROSPERO database, as it qualifies as a literature review (scoping reviews, literature reviews, or mapping reviews do not qualify for PROSPERO registration). The review outcomes focused on the inclusion of course content and assessing the benefits of trauma education courses using provider- and patient-based metrics. Provider outcomes were defined as knowledge, skill level, confidence, and comfort with the material. Patient-based outcomes were defined as mortality and morbidity rates of trauma patients after implementation of a trauma course.

The search strategy was performed in MEDLINE, Scopus, Web of Science, CINAHL, Cochrane Reviews, Cochrane Trials, and Global Index Medicus. The search algorithm is available in Appendix 1 of the Online Supplementary Document. All identified titles and abstracts were assessed based on screening criteria listed in Table 1. The initial analysis was conducted through the Rayyan: Intelligent Systematic Review online platform [27]. The review was conducted by four individual reviewers (JR, JB, SB, YS), and one tiebreaker reviewer (MS). Secondary analysis consisted of a review of included articles by the same reviewers and tiebreaker based on the above criteria.

Table 1.  Inclusion criteria for the literature review of paediatric trauma education

ATLS – Advanced Trauma Life Support, TEAM – Trauma Education and Management, PTC – Primary Trauma Care, TTT – Trauma Team Training

Data from included articles were extracted onto an Excel spreadsheet. Recorded information included authors, publication year, country, institution, type of trauma course used, number and type of participations, and outcomes. Data was reviewed for accuracy by four independent reviewers.

There is no standardized trauma curriculum or tool for evaluation of medical curriculum content. Initial evaluation of programmes included year of development, teaching method, cost per student or course, length of course, equipment required, and course content, particularly the inclusion of paediatric focused teaching. Course content was then compared based on topics and procedures in ATLS. Each course was assessed for teaching modality (didactic, hands on, and simulation-based learning). The assessed content included primary survey, secondary survey, airway and ventilation, circulation, shock, thoracic trauma, head/spinal trauma, abdomen/pelvis trauma, musculoskeletal trauma, paediatric trauma, geriatric trauma, obstetric trauma, transfer of care, and other course specific inclusions. Courses were also assessed for inclusion of ATLS-based procedural skills (intubation, ventilation, intraosseous (IO) access, chest tube placement, focused assessment in sonography in trauma (FAST) exam, spinal stabilization, and musculoskeletal splinting).

Each study was assessed for bias using the Risk Of Bias In Non-randomized Studies of Interventions (ROBINS-I) [28]. Bias evaluation was scored as low risk of bias (score of 3), moderate risk of bias (score of 2), serious risk of bias (score of 1), or no information (score of 0). These assessments were based on seven bias domains (bias due to confounding, bias in selection of participants into the study, bias in classification of interventions, bias due to deviations from intended interventions, bias due to missing data, bias in measurement of outcomes, and bias in selection of the reported results). All articles were scored by at least two reviewers (JR, JB, SB, YS) and one tiebreaker reviewer (MS), as needed. Bias domain scores were then averaged to provide a total bias evaluation score.

RESULTS

The database search yielded 2008 records with 987 included for review after deduplication; among them, 63 articles were found eligible for full-text review according to revised criteria (excluded non-English studies, high-income countries, prehospital settings, or personnel). Thirty-nine studies were included for qualitative synthesis and analysis. The PRISMA diagram of the literature search is shown in Figure 1.

Figure 1.  PRISMA diagram for the paediatric trauma literature review.

All 39 studies included course-specific content; 33 studies focused on provider-based outcomes and six evaluated patient-directed outcomes. Study summaries are included in Table 2. Included articles were published between 1992 and 2022 and originated from 25 countries (six Asian, eight North and South American, and 14 African).

Table 2.  Summary of included papers in paediatric trauma literature review

ATLS – Advance Trauma Life Support, TEAM – Trauma Education and Management, PTC – Primary Trauma Care, BTCC – Basic Trauma Care Course, EWMT – Emergency Ward Management of Trauma, TTT – Trauma Team Training, APLS – Advanced Paediatric Life Support, EMEI – Emergency Medicine Education Intervention, BTLS – Basic Trauma Life Support, ACT – Acute Trauma Care, FCCS – Fundamental Critical Care Support, COSECA – College of Surgeons of East, Central, and Southern Africa (Burundi, Ethiopia, Kenya, Malawi, Mozambique, Rwanda, Tanzania, Uganda, Zambia, Zimbabwe), NTC – Nicaraguan Trauma Course, EPPTC Essential Principles and Practices of Trauma Care, KATC – Kampala Advanced Trauma Course, MTTC – Myanmar Trauma Training Course, JPTC – Jamaican Pediatric Trauma Course, STEPs – Sequential Trauma Education Programs Course, MCQ – multiple choice question, OSCE – Objective Structured Clinical Examination, MR – mortality ratio, CI – confidence interval, OR – odds ratio, LMIC – low- and middle-income countries, HIC – high-income countries

Sixteen trauma training programmes were identified in the included studies and are summarized in Table 3. All courses discussed primary/secondary surveys, airway and ventilation, and shock. Of the six assessed hands-on skills, only intubation and advance airway management were provided by all programmes. Table 4 provides a summary of the examined curriculum components. Two of the 16 curricula were solely for paediatric trauma (Advanced Paediatric Life Support (APLS) and the Jamaican Pediatric Trauma Course (JPTC)) [41,62]. There were seven programmes with paediatric discussion sections that consisted of 20-30-minute lectures within courses that lasted one to five days. Paediatric-specific skills were only covered in the two programmes solely devoted to paediatric care. All courses had varying levels of inclusion of the remaining topics (Table 4). Four curricula included additional content specific to the region; for example, two discussed snake bites (Basic Trauma Care Course (BTCC) and Trauma Team Training (TTT)), and one covered burr holes (Kampala Advanced Trauma Course (KATC)) for head trauma. One was reported to have more extensive coverage of topics specific to paediatric populations, such as situational awareness (like area safety), nutrition, mental health, sedation, suturing, and blood transfusions (Myanmar Trauma Training Course (MTTC)).

Table 3.  Summary of the included curricula in paediatric trauma literature review

ATLS – Advance Trauma Life Support, TEAM – Trauma Education and Management, PTC – Primary Trauma Care, BTCC – Basic Trauma Care Course, EWMT – Emergency Ward Management of Trauma, TTT – Trauma Team Training, APLS – Advanced Paediatric Life Support, EMEI – Emergency Medicine Education Intervention, BTLS – Basic Trauma Life Support, ACT – Acute Trauma Care, FCCS – Fundamental Critical Care Support, COSECA – College of Surgeons of East, Central, and Southern Africa (Burundi, Ethiopia, Kenya, Malawi, Mozambique, Rwanda, Tanzania, Uganda, Zambia, Zimbabwe), NTC – Nicaraguan Trauma Course, EPPTC Essential Principles and Practices of Trauma Care, KATC – Kampala Advanced Trauma Course, MTTC – Myanmar Trauma Training Course, JPTC – Jamaican Pediatric Trauma Course, STEPs – Sequential Trauma Education Programs Course

Table 4.  Breakdown of the 16 curricula based on teaching method and content

ATLS – Advance Trauma Life Support, TEAM – Trauma Education and Management, PTC – Primary Trauma Care, BTCC – Basic Trauma Care Course, EWMT – Emergency Ward Management of Trauma, TTT – Trauma Team Training, APLS – Advanced Paediatric Life Support, EMEI – Emergency Medicine Education Intervention, BTLS – Basic Trauma Life Support, ACT – Acute Trauma Care, FCCS – Fundamental Critical Care Support, COSECA – College of Surgeons of East, Central, and Southern Africa (Burundi, Ethiopia, Kenya, Malawi, Mozambique, Rwanda, Tanzania, Uganda, Zambia, Zimbabwe), NTC – Nicaraguan Trauma Course, EPPTC Essential Principles and Practices of Trauma Care, KATC – Kampala Advanced Trauma Course, MTTC – Myanmar Trauma Training Course, JPTC – Jamaican Pediatric Trauma Course, STEPs – Sequential Trauma Education Programs Course, FAST – Focused Assessment with Sonography in Trauma

Course evaluations were administered through provider-based or patient-based metrics (Table 2). Provider-based metrics consisted of pre- and post-course assessments of knowledge using multiple choice questions (MCQs), hands-on experience with procedures, trauma scenario simulations, and objective structured clinical examinations (OSCEs). Providers were also surveyed for knowledge and confidence with trauma care. Twenty-two studies reported use of pre- and post-intervention MCQs for knowledge assessment, with all participants demonstrating knowledge acquisition [20,21,3239,42,44,46,4851,5355,57,58]. Four programmes utilized OSCE assessments [22,29,31,33], and five used simulation and hands-on skills assessments [21,37,42,51,55]. Thirteen programmes used surveys to assess provider-perceived knowledge attainment [20,32,34,36,40,4547,50,53,60,61], and nine used surveys to assess providers’ confidence in their skills [45,49,50,52,54,56,5861].

ATLS was used by six programmes with patient-based metrics [15,17,30,37,44]. Four of these studies reported case fatality rates pre- and post- ATLS course implementation [15,17,30,37]. Heydari et al. evaluated morbidity according to time to physician attendance (P < 0.001), intubation rates (P = 0.01), and length of time to hospital transfer (P < 0.001) [44]. Petroze et al. evaluated trauma registry data in Rwanda after ATLS and TTT implementation [17], showing a decline in case fatality from 8.8 to 6.3% (P = 0.09) after implementation of both ATLS and TTT. Case fatality rates for patients with Glasgow Coma Scale (GCS) results <8 decreased from 58.5% to 37.1% (P = 0.009). There was no difference in rates of early intubation, cervical collar use, imaging, or transfusion. Only one study did not find a significant change in case fatality rate after implementation of ATLS. Ariyanayagam et al. [37] reported traffic injury case fatality rates of 49% pre-ATLS training and 46% post ATLS training (P-value not reported).

One study reported patient-based metrics using the Sequential Trauma Education Program course (STEPs) [42]. Elbaih et al. reported a number of missed injuries and missed vital data recording on patients with multiple-trauma. After implementing STEPs, the number of missed injuries did not significantly decrease (12.0% to 9.0%, P = 0.338). However, missed vital data recording significantly improved with decreases in missed recordings in heart rate (60% to 0%, P < 0.001), blood pressure (46.7% to 0%, P < 0.001), and respiratory rate (60% to 0%, P < 0.001).

ROBINS-I tool bias evaluation scores ranged from 1.4 to 2 out of 3 for all studies. Bias scores mostly reflected concerns for confounding and missing data. Most studies we reviewed were informal evaluations performed after trauma course implementation. Statistical analysis focused on participant score improvement without detailed qualitative analysis. No studies were randomized controlled trials.

DISCUSSION

We aimed to gather information on existing trauma curricula regarding inclusion of paediatric training in courses in LMICs. We found that, while trauma curricula in LMICs positively impacted provider knowledge and decreased trauma-related morbidity and mortality, they significantly lack paediatric-focused education.

Our review identified 39 studies that reported on 16 unique trauma training programmes. All reported improvements in provider-based metrics, and the majority reported improvements in patient morbidity and mortality outcomes. These data reinforce the importance and utility of trauma curricula in LMIC in improving trauma-related outcomes [2,6,13,14]. However, only half of studies reviewed here included paediatric content, emphasizing a gap in current LMIC educational practices that impact nearly 20% of the global trauma patient population [2,3].

Most trauma providers in LMICs will treat both adult and paediatric patients. As a result, trauma courses, such as ATLS, PTC, and TEAM, may be directed toward adult care with variable inclusion of paediatrics. Seven of the 16 courses examined in our review do not discuss paediatric trauma. In those courses with supplementary paediatric material, this instruction consists of only 20 to 30 minutes during one-to-five-day courses. This is very limited amount of time to cover material that is very distinct from adult care.

Children have rapidly changing physiology that alters the effect of injury mechanism, metabolism, and medication dosing. Airways are more anterior, requiring different intubation techniques. Small children are more susceptible to multiorgan injury in blunt trauma. With higher metabolism and lower physiologic reserves, children are at risk of hypothermia, hypoglycaemia, and more rapid decompensation. As a child grows, normal vital sign ranges shift and medications require weight-based dosing. Children are more prone to respiratory arrest causing cardiac arrest, altering how resuscitation methods are done [63]. Without an understanding of paediatric physiology and trauma management, providers lack the necessary tools to care for 20% of the global trauma population [2,3].

The breadth of paediatric trauma content is illustrated in the two courses found to be specific for this training. Wesson et al.’s [62] report on the JPTC described a full day course that covers management of paediatric airway, shock, head injury, thoracic/abdominal injury, burns, and paediatric trauma resuscitation. Procedural skills in intubation and ventilation were included. The APLS course, described by in Dhingra et al. [41], is a two-day course that covers content similar to that of the JPTC but includes care of musculoskeletal injuries, IO access, chest tube placement, and spinal stabilization. While there are overlaps in content with adult material, reduction of a one-to-two-day course into 20-30 minutes results seems to be insufficient.

To understand the extent of this educational deficiency, it is necessary to evaluate individual programme content. All trauma curricula covered airway, breathing, and circulation with primary and secondary trauma surveys. Additional subjects included in courses varied based on country of origin, materials available, and site needs assessments [7,22]. Due to this lack of standardization, it is difficult to fully compare curricula.

In a similar assessment of paediatric inclusion in trauma education in LMICs, Pinkham et al. also found an absence of internationally recognized paediatric trauma training programmes. They identified eight distinct courses (Emergency Triage, Assessment and Treatment plus Admission (ETAT+), Adapted Emergency Triage, Assessment, and Treatment (ETAT), Adapted Primary Trauma Care Course, Core Topics in Pediatric Emergency Care, Bastion Trauma Course, Pediatric Fundamental Critical Care Support, and two institutional paediatric trauma courses) [24]. All courses identified by Pinkham et al. were different from those found by this review, highlighting the variability in existing educational options.

Pinkham et al.’s [24] courses were assessed based on training modality, assessment methods, and outcomes. To assess the effectiveness of the identified courses, they used the Kirkpatrick’s Framework for Trauma Courses. The Kirkpatrick scale ranks courses based on four levels of efficacy focusing on participant perceptions, knowledge attainment, skills attainment, and patient-based metrics [64].

Per the provider- and patient-based metrics included in our assessment of 36 programmes, all demonstrated at least level 3-4 of curriculum efficacy based on the Kirkpatrick system. While this supports the generally positive impact of the reported curricula, the variability in the coverage may reduce the transferability among diverse settings and learner populations. If a standardized paediatric trauma curriculum could be developed, this content could be disseminated widely through distance-based learning and could be adapted based on local needs assessments allowing for improved efficacy and reliability of clinical care. To our knowledge, there is no standardized paediatric trauma curriculum geared to LMICs nor a formal method of evaluating the efficacy of such training.

Limitations

There are some limitations to this systematic literature review. The broad search criteria resulted in less rigorous studies being included, opening the review to inclusion bias and raising concerns for the lack of evidentiary data. We aimed to evaluate current curricula on paediatric trauma available in LMICs. While our search was intentionally broad, it likely does not include all paediatric trauma trainings. The evaluation of curricular content and outcomes was also limited due to variable information included in the studies. A curricular content assessment tool is needed to evaluate courses with a standardized approach. Both the paucity of paediatric-focused trauma education and medical curriculum content evaluation tools limit the ability to address gaps in paediatric trauma training in LMICs. Nevertheless, this literature review shows a lack of paediatric-focused trauma education and high variability in curriculum content without a systematic means of assessment.

CONCLUSIONS

Trauma curricula in LMICs have been shown to decrease trauma-related mortality and positively impact provider knowledge. However, there is a dearth of education focused on paediatric trauma. Current curricular reports describe high variability in content, making it difficult to transfer or evaluate educational efforts among diverse learner populations. This curricular deficiency also falls short of the training needs necessary for providers to care for children, who are 20% of the global trauma patient population and who have a 32% preventable death rate related to trauma injuries [2,3,25]. Further work is needed in curriculum assessment tools and paediatric-focused trauma education. We plan to use the findings in this review to develop a novel paediatric trauma curriculum specific to resource-limited settings. This course will utilize provider and patient-based metrics to track its impact on a regional trauma care. Continuing the advancement of paediatric trauma education will help to protect this vulnerable patient population and reduce the global burden of disease caused by traumatic injuries.

Additional Materials:

Online Supplementary Document

Acknowledgements

Thank you to Danny G. Thomas MD, MPH, of the Medical College of Wisconsin for his guidance in the process of creating this manuscript, and thank you to Elizabeth Suelzer MLIS, of the Medical College of Wisconsin for her assistance in compiling the search results for the literature review.

Data availability: Data reported in this manuscript can be obtained through contact with the corresponding author.

[1] Funding: The research presented in this manuscript received to external funding.

[2] Authorship contributions: Jane A Rivas: primary author, contributor and editor. Contributed substantially to the acquisition, analysis, and interpretation of data for the manuscript. Drafted and revised the manuscript critically. Provided final approval of the version to be published. Agrees to be accountable for all aspects of the work. Joseph Bartoletti: contributed substantially to the acquisition, analysis, and interpretation of data for the manuscript. Sarah Bennett: contributed substantially to the acquisition, analysis, and interpretation of data for the manuscript. Yukino Strong: contributed substantially to the acquisition, analysis, and interpretation of data for the manuscript. Thomas E Novotny: revised the manuscript critically. Provided approval of the version to be published. Megan L Schultz: contributed substantially to the acquisition, analysis, and interpretation of data for the manuscript. Revised the manuscript critically. Provided approval of the version to be published.

[3] Disclosure of interest: The authors completed the ICMJE Disclosure of Interest Form (available upon request from the corresponding author) and declare the following activities and relationships: Thomas Novotny, MD, MPH declares the following activities and relationships: research and funding through the California Department of Public Health, the World Health Organization, the University of California Tobacco-related Disease Research Program, the United States Food and Drug Administration consulting, World Scientific Publishers, the San Francisco Estuary Institute, the University of San Francisco School of Medicine, the London School of Hygiene and Tropical Medicine, and he is the current CEO of Cigarette Butt Pollution Project.

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Correspondence to:
Jane A Rivas, MD
Medical College of Wisconsin
Milwaukee, Wisconsin
United States of America
[email protected]